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Cistrome-based Cooperation between Airway Epithelial Glucocorticoid Receptor and NF-κB Orchestrates Anti-inflammatory Effects

Antagonism of pro-inflammatory transcription factors by monomeric glucocorticoid receptor (GR) has long been viewed as central to glucocorticoid (GC) efficacy. However, the mechanisms and targets through which GCs exert therapeutic effects in diseases such as asthma remain incompletely understood. W...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Kadiyala, Vineela, Sasse, Sarah K., Altonsy, Mohammed O., Berman, Reena, Chu, Hong W., Phang, Tzu L., Gerber, Anthony N.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933445/
https://ncbi.nlm.nih.gov/pubmed/27076634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.721217
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