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Examining the Effects of Sodium Ions on the Binding of Antagonists to Dopamine D(2) and D(3) Receptors

Many G protein-coupled receptors have been shown to be sensitive to the presence of sodium ions (Na(+)). Using radioligand competition binding assays, we have examined and compared the effects of sodium ions on the binding affinities of a number of structurally diverse ligands at human dopamine D(2)...

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發表在:PLoS One
Main Authors: Newton, Claire L., Wood, Martyn D., Strange, Philip G.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933336/
https://ncbi.nlm.nih.gov/pubmed/27379794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158808
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