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Examining the Effects of Sodium Ions on the Binding of Antagonists to Dopamine D(2) and D(3) Receptors
Many G protein-coupled receptors have been shown to be sensitive to the presence of sodium ions (Na(+)). Using radioligand competition binding assays, we have examined and compared the effects of sodium ions on the binding affinities of a number of structurally diverse ligands at human dopamine D(2)...
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| Publicado no: | PLoS One |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4933336/ https://ncbi.nlm.nih.gov/pubmed/27379794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158808 |
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