Proteomic Characterization of Inhibitory Synapses Using a Novel pHluorin-tagged γ-Aminobutyric Acid Receptor, Type A (GABA(A)), α2 Subunit Knock-in Mouse

The accumulation of γ-aminobutyric acid receptors (GABA(A)Rs) at the appropriate postsynaptic sites is critical for determining the efficacy of fast inhibitory neurotransmission. Although we know that the majority of synaptic GABA(A)R subtypes are assembled from α1–3, β, and γ2 subunits, our underst...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Nakamura, Yasuko, Morrow, Danielle H., Modgil, Amit, Huyghe, Deborah, Deeb, Tarek Z., Lumb, Michael J., Davies, Paul A., Moss, Stephen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Neurobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933285/
https://ncbi.nlm.nih.gov/pubmed/27044742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.724443
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