Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R)

The glucagon-like peptide-1 receptor (GLP-1R) belongs to the secretin-like (class B) family of G protein-coupled receptors. Members of the class B family are distinguished by their large extracellular domain, which works cooperatively with the canonical seven-transmembrane (7TM) helical domain to si...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Yang, Dehua, de Graaf, Chris, Yang, Linlin, Song, Gaojie, Dai, Antao, Cai, Xiaoqing, Feng, Yang, Reedtz-Runge, Steffen, Hanson, Michael A., Yang, Huaiyu, Jiang, Hualiang, Stevens, Raymond C., Wang, Ming-Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933217/
https://ncbi.nlm.nih.gov/pubmed/27059958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.721977
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