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A1 adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells.

A1 adenosine-receptor-antagonist drugs such as 8-cyclopentyl-1,3-dipropylxanthine (CPX) and xanthine amine congener (XAC) are found to activate the efflux of 36Cl- from CFPAC cells. These cells are a pancreatic adenocarcinoma cell line derived from a cystic fibrosis (CF) patient homozygous for the c...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Eidelman, O, Guay-Broder, C, van Galen, P J, Jacobson, K A, Fox, C, Turner, R J, Cabantchik, Z I, Pollard, H B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49332/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1376923/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.12.5562
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