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Lysosomal Dysfunction Caused by Cellular Accumulation of Silica Nanoparticles

Nanoparticles (NPs) are widely used as components of drugs or cosmetics and hold great promise for biomedicine, yet their effects on cell physiology remain poorly understood. Here we demonstrate that clathrin-independent dynamin 2-mediated caveolar uptake of surface-functionalized silica nanoparticl...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Schütz, Irene, Lopez-Hernandez, Tania, Gao, Qi, Puchkov, Dmytro, Jabs, Sabrina, Nordmeyer, Daniel, Schmudde, Madlen, Rühl, Eckart, Graf, Christina M., Haucke, Volker
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933175/
https://ncbi.nlm.nih.gov/pubmed/27226546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710947
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