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Lysosomal Dysfunction Caused by Cellular Accumulation of Silica Nanoparticles

Nanoparticles (NPs) are widely used as components of drugs or cosmetics and hold great promise for biomedicine, yet their effects on cell physiology remain poorly understood. Here we demonstrate that clathrin-independent dynamin 2-mediated caveolar uptake of surface-functionalized silica nanoparticl...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Schütz, Irene, Lopez-Hernandez, Tania, Gao, Qi, Puchkov, Dmytro, Jabs, Sabrina, Nordmeyer, Daniel, Schmudde, Madlen, Rühl, Eckart, Graf, Christina M., Haucke, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933175/
https://ncbi.nlm.nih.gov/pubmed/27226546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710947
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