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Fragile X Mental Retardation Protein (FMRP) controls diacylglycerol kinase activity in neurons

Fragile X syndrome (FXS) is caused by the absence of the Fragile X Mental Retardation Protein (FMRP) in neurons. In the mouse, the lack of FMRP is associated with an excessive translation of hundreds of neuronal proteins, notably including postsynaptic proteins. This local protein synthesis deregula...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Tabet, Ricardos, Moutin, Enora, Becker, Jérôme A. J., Heintz, Dimitri, Fouillen, Laetitia, Flatter, Eric, Krężel, Wojciech, Alunni, Violaine, Koebel, Pascale, Dembélé, Doulaye, Tassone, Flora, Bardoni, Barbara, Mandel, Jean-Louis, Vitale, Nicolas, Muller, Dominique, Le Merrer, Julie, Moine, Hervé
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932937/
https://ncbi.nlm.nih.gov/pubmed/27233938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522631113
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