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Fragile X Mental Retardation Protein (FMRP) controls diacylglycerol kinase activity in neurons

Fragile X syndrome (FXS) is caused by the absence of the Fragile X Mental Retardation Protein (FMRP) in neurons. In the mouse, the lack of FMRP is associated with an excessive translation of hundreds of neuronal proteins, notably including postsynaptic proteins. This local protein synthesis deregula...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tabet, Ricardos, Moutin, Enora, Becker, Jérôme A. J., Heintz, Dimitri, Fouillen, Laetitia, Flatter, Eric, Krężel, Wojciech, Alunni, Violaine, Koebel, Pascale, Dembélé, Doulaye, Tassone, Flora, Bardoni, Barbara, Mandel, Jean-Louis, Vitale, Nicolas, Muller, Dominique, Le Merrer, Julie, Moine, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932937/
https://ncbi.nlm.nih.gov/pubmed/27233938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522631113
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