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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

Control elements of the tetracycline-resistance operon encoded in Tn10 of Escherichia coli have been utilized to establish a highly efficient regulatory system in mammalian cells. By fusing the tet repressor with the activating domain of virion protein 16 of herpes simplex virus, a tetracycline-cont...

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Библиографические подробности
Главные авторы: Gossen, M, Bujard, H
Формат: Artigo
Язык:Inglês
Опубликовано: 1992
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC49329/
https://ncbi.nlm.nih.gov/pubmed/1319065
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