Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
Control elements of the tetracycline-resistance operon encoded in Tn10 of Escherichia coli have been utilized to establish a highly efficient regulatory system in mammalian cells. By fusing the tet repressor with the activating domain of virion protein 16 of herpes simplex virus, a tetracycline-cont...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1992
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49329/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1319065/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.12.5547 |
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