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Immunoelectron microscopic localization of the ubiquitin-activating enzyme E1 in HepG2 cells.

As the first enzyme in the ubiquitin system the ubiquitin-activating enzyme E1 plays a pivotal role in all pathways of protein ubiquitination. In an effort to learn more about the cell biology of this pathway, we have purified the 110-kDa enzyme to homogeneity and generated a panel of distinct monoc...

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Autors principals: Schwartz, A L, Trausch, J S, Ciechanover, A, Slot, J W, Geuze, H
Format: Artigo
Idioma:Inglês
Publicat: 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC49328/
https://ncbi.nlm.nih.gov/pubmed/1376922
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