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Immunoelectron microscopic localization of the ubiquitin-activating enzyme E1 in HepG2 cells.

As the first enzyme in the ubiquitin system the ubiquitin-activating enzyme E1 plays a pivotal role in all pathways of protein ubiquitination. In an effort to learn more about the cell biology of this pathway, we have purified the 110-kDa enzyme to homogeneity and generated a panel of distinct monoc...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Schwartz, A L, Trausch, J S, Ciechanover, A, Slot, J W, Geuze, H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49328/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1376922/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.12.5542
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