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Self-Assembly of Amphiphilic Dendrimers: The Role of Generation and Alkyl Chain Length in siRNA Interaction

An ideal nucleic-acid transfection system should combine the physical and chemical characteristics of cationic lipids and linear polymers to decrease cytotoxicity and uptake limitations. Previous research described new types of carriers termed amphiphilic dendrimers (ADs), which are based on polyami...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Márquez-Miranda, Valeria, Araya-Durán, Ingrid, Camarada, María Belén, Comer, Jeffrey, Valencia-Gallegos, Jesús A., González-Nilo, Fernando Danilo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932498/
https://ncbi.nlm.nih.gov/pubmed/27377641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29436
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