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The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model
A central question in Alzheimer's Disease (AD) is whether the neuritic plaque is necessary and sufficient for the development of tau pathology. Hyperphosphorylation of tau is found within dystrophic neurites surrounding β-amyloid deposits in AD mouse models but the pathological conversion of ta...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932197/ https://ncbi.nlm.nih.gov/pubmed/27373369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12082 |
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