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Fast exchange fluxes around the pyruvate node: a leaky cell model to explain the gain and loss of unlabelled and labelled metabolites in a tracer experiment

BACKGROUND: Glucose and glutamine are the two dominant metabolic substrates in cancer cells. In (13)C tracer experiments, however, it is necessary to account for all significant input substrates, as some natural (unlabelled) substrate in the medium, often derived from serum, can be metabolised by ce...

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Detalhes bibliográficos
Publicado no:Cancer Metab
Main Authors: Quek, Lake-Ee, Liu, Menghan, Joshi, Sanket, Turner, Nigel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931697/
https://ncbi.nlm.nih.gov/pubmed/27379180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-016-0153-9
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