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Effects of KLK Peptide on Adjuvanticity of Different ODN Sequences

Endosomal Toll-like receptors (TLR) such as TLR3, 7, 8 and 9 recognize pathogen associated nucleic acids. While DNA sequence does influence degree of binding to and activation of TLR9, it also appears to influence the ability of the ligand to reach the intracellular endosomal compartment. The KLK (K...

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Podrobná bibliografie
Vydáno v:Vaccines (Basel)
Hlavní autoři: Chikh, Ghania, Luu, Rachel, Patel, Shobhna, Davis, Heather L., Weeratna, Risini D.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931631/
https://ncbi.nlm.nih.gov/pubmed/27153098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines4020014
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