UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly

Early eukaryotic ribosome biogenesis involves large multi-protein complexes, which co-transcriptionally associate with pre-ribosomal RNA to form the small subunit processome. The precise mechanisms by which two of the largest multi-protein complexes—UtpA and UtpB—interact with nascent pre-ribosomal...

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Pubblicato in:Nat Commun
Autori principali: Hunziker, Mirjam, Barandun, Jonas, Petfalski, Elisabeth, Tan, Dongyan, Delan-Forino, Clémentine, Molloy, Kelly R., Kim, Kelly H., Dunn-Davies, Hywel, Shi, Yi, Chaker-Margot, Malik, Chait, Brian T., Walz, Thomas, Tollervey, David, Klinge, Sebastian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931317/
https://ncbi.nlm.nih.gov/pubmed/27354316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12090
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