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The decision‐making process and criteria in selecting candidate drugs for progeria clinical trials
Hutchinson–Gilford progeria syndrome (progeria) is an extremely rare premature aging disease with a population prevalence of 1 in 20 million. Nevertheless, propelled by the discovery of a causal mutation in the lamin A/C gene (LMNA) (De Sandre‐Giovannoli et al, 2003; Eriksson et al, 2003) and strong...
Shranjeno v:
| izdano v: | EMBO Mol Med |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4931284/ https://ncbi.nlm.nih.gov/pubmed/27234439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606280 |
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