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MYC/MIZ1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation

The circadian clock and the cell cycle are major cellular systems that organize global physiology in temporal fashion. It seems conceivable that the potentially conflicting programs are coordinated. We show here that overexpression of MYC in U2OS cells attenuates the clock and conversely promotes ce...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Shostak, Anton, Ruppert, Bianca, Ha, Nati, Bruns, Philipp, Toprak, Umut H., Eils, Roland, Schlesner, Matthias, Diernfellner, Axel, Brunner, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931031/
https://ncbi.nlm.nih.gov/pubmed/27339797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11807
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