Triptolide Inhibits Osteoclast Differentiation and Bone Resorption In Vitro via Enhancing the Production of IL-10 and TGF-β1 by Regulatory T Cells

Triptolide, a purified component of Tripterygiumwilfordii Hook F, has been shown to have immunosuppressive and anti-inflammatory properties in rheumatoid arthritis (RA). Although triptolide has demonstrated that it could suppress bone destruction in collagen-induced mice, its therapeutic mechanism r...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Xu, Huihui, Zhao, Hongyan, Lu, Cheng, Qiu, Qi, Wang, Gui, Huang, Jing, Guo, Minghui, Guo, Baosheng, Tan, Yong, Xiao, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930824/
https://ncbi.nlm.nih.gov/pubmed/27413257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8048170
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