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HIV-1 tat and rev upregulates osteoclast bone resorption

INTRODUCTION: Disruption in bone homeostasis with increased osteoclastic resorption may lead to osteoporosis. HIV tat has been found to increase differentiation of precursor cells into osteoclast (OC) [1]. Presence of soluble HIV proteins in virally suppressed HIV patients on ART may drive a bone re...

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Detalhes bibliográficos
Publicado no:J Int AIDS Soc
Main Authors: Chew, Nicholas, Tan, Eemin, Li, Lei, Lim, Ryan
Formato: Artigo
Idioma:Inglês
Publicado em: International AIDS Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225338/
https://ncbi.nlm.nih.gov/pubmed/25397470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7448/IAS.17.4.19724
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