Characterization of the binding pattern of human aquaporin-4 autoantibodies in patients with neuromyelitis optica spectrum disorders

BACKGROUND: The discovery of a highly specific antibody against the aquaporin-4 (AQP4) water channel (AQP4-IgG) unified the spectrum of neuromyelitis optica spectrum disorders (NMOSD), which are considered to be antibody-mediated autoimmune diseases. The AQP4 water channel is located on astrocytic e...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Tuller, Friederike, Holzer, Hannah, Schanda, Kathrin, Aboulenein-Djamshidian, Fahmy, Höftberger, Romana, Khalil, Michael, Seifert-Held, Thomas, Leutmezer, Fritz, Berger, Thomas, Reindl, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930584/
https://ncbi.nlm.nih.gov/pubmed/27371173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0642-3
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