Reduction in Serum Aquaporin-4 Antibody Titers During Development of a Tumor-Like Brain Lesion in a Patient With Neuromyelitis Optica: A Serum Antibody–Consuming Effect?

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the CNS with severe involvement of the optic nerve and spinal cord. Highly specific serum IgG autoantibodies (NMO-IgG) that react with aquaporin-4 (AQP4), the most abundant CNS water channel protein, are found in patients with NM...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Aboulenein-Djamshidian, Fahmy, Höftberger, Romana, Waters, Patrick, Krampla, Wolfgang, Lassmann, Hans, Budka, Herbert, Vincent, Angela, Kristoferitsch, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Association of Neuropathologists 2015
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327561/
https://ncbi.nlm.nih.gov/pubmed/25668569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0000000000000173
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