Downregulation of human Wnt3 in gastric cancer suppresses cell proliferation and induces apoptosis

Aberrant activation of Wnt/β-catenin signaling pathways is closely involved in the occurrence and progression of several types of human malignancies. However, as a fundamental component in this cascade, Wnt3 has not been well understood for the expression level and pathogenic mechanism in gastric ca...

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Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Wang, Hai-Sheng, Nie, Xiaobo, Wu, Rui-Bing, Yuan, Hong-Wei, Ma, Yue-Hong, Liu, Xiu-Lan, Zhang, Jian-Yu, Deng, Xiu-Ling, Na, Qin, Jin, Hai-Yan, Bian, Yan-Chao, Gao, Yu-Min, Wang, Yan-Dong, Chen, Wei-Dong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930241/
https://ncbi.nlm.nih.gov/pubmed/27390525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S101782
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