Downregulation of Wnt3 Suppresses Colorectal Cancer Development Through Inhibiting Cell Proliferation and Migration

The aberrant expression of Wnt3 has linked to several types of human malignancies. However, it is not known for its role in tumorigenesis of colorectal cancer (CRC). Herein, we show that Wnt3 is upregulated in human CRC tissues and is essential for the CRC progression. Knockdown of Wnt3 in human CRC...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Nie, Xiaobo, Xia, Fulin, Liu, Ying, Zhou, Yun, Ye, Wenling, Hean, Panha, Meng, Jiming, Liu, Huiyang, Liu, Lei, Wen, Jianxun, Ren, Xuequn, Chen, Wei-Dong, Wang, Yan-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779829/
https://ncbi.nlm.nih.gov/pubmed/31632267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01110
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