It All Starts with a Sandwich: Identification of Sialidases with Trans-Glycosylation Activity

Sialidases (3.2.1.18) may exhibit trans-sialidase activity to catalyze sialylation of lactose if the active site topology is congruent with that of the Trypanosoma cruzi trans-sialidase (EC 2.4.1.-). The present work was undertaken to test the hypothesis that a particular aromatic sandwich structure...

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Pubblicato in:PLoS One
Autori principali: Nordvang, Rune T., Nyffenegger, Christian, Holck, Jesper, Jers, Carsten, Zeuner, Birgitte, Sundekilde, Ulrik K., Meyer, Anne S., Mikkelsen, Jørn D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930215/
https://ncbi.nlm.nih.gov/pubmed/27367145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158434
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