MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma

Microtubule inhibitors have been shown to inhibit Janus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) signal transduction pathway in various cancer cells. However, little is known of the mechanism by which the microtubule inhibitors inhibit STAT3 activity. In the present s...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Peng, Hsuan-Yu, Cheng, Yun-Ching, Hsu, Yuan-Ming, Wu, Guan-Hsun, Kuo, Ching-Chuan, Liou, Jing-Ping, Chang, Jang-Yang, Jin, Shiow-Lian Catherine, Shiah, Shine-Gwo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930189/
https://ncbi.nlm.nih.gov/pubmed/27367272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158440
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