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A simple physical mechanism enables homeostasis in primitive cells

The emergence of homeostatic mechanisms that enabled maintenance of an intracellular steady-state during growth was critical to the advent of cellular life. Here, we show that concentration-dependent reversible binding of short oligonucleotides, of both specific and random sequence, can modulate rib...

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Detalhes bibliográficos
Publicado no:Nat Chem
Main Authors: Engelhart, Aaron E., Adamala, Katarzyna, Szostak, Jack W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929987/
https://ncbi.nlm.nih.gov/pubmed/27102678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2475
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