Abnormalities of follicular helper T-cell number and function in Wiskott-Aldrich syndrome

Wiskott-Aldrich syndrome protein (WASp) is a hematopoietic-specific regulator of actin nucleation. Wiskott-Aldrich syndrome (WAS) patients show immunodeficiencies, most of which have been attributed to defective T-cell functions. T follicular helper (Tfh) cells are the major CD4(+) T-cell subset wit...

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Veröffentlicht in:Blood
Hauptverfasser: Zhang, Xuan, Dai, Rongxin, Li, Wenyan, Zhao, Hongyi, Zhang, Yongjie, Zhou, Lina, Du, Hongqiang, Luo, Guangjin, Wu, Junfeng, Niu, Linlin, An, Yunfei, Zhang, Zhiyong, Ding, Yuan, Song, Wenxia, Liu, Chaohong, Zhao, Xiaodong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2016
Schlagworte:
Immunobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929975/
https://ncbi.nlm.nih.gov/pubmed/27170596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-06-652636
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