The early activation of memory B cells from Wiskott-Aldrich syndrome patients is suppressed by CD19 downregulation

Wiskott-Aldrich syndrome (WAS) pediatric patients exhibit a deficiency in humoral immune memory. However, the mechanism by which Wiskott-Aldrich syndrome protein (WASP) regulates the differentiation and activation of memory B cells remains elusive. Here we examine the early activation events of memo...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Bai, Xiaoming, Zhang, Yongjie, Huang, Lu, Wang, Jinzhi, Li, Wenyan, Niu, Linlin, Jiang, Hongyan, Dai, Rongxin, Zhou, Lina, Zhang, Zhiyong, Miller, Heather, Song, Wenxia, Zhao, Xiaodong, Liu, Chaohong
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2016
Matèries:
Immunobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043127/
https://ncbi.nlm.nih.gov/pubmed/27330000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-703579
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