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CCL5 activation of CCR5 regulates cell metabolism to enhance proliferation of breast cancer cells

In earlier studies, we showed that CCL5 enhances proliferation and survival of MCF-7 breast cancer cells in an mTOR-dependent manner and we provided evidence that, for T cells, CCL5 activation of CCR5 results in increased glycolysis and enhanced ATP production. Increases in metabolic activity of can...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Gao, Darrin, Rahbar, Ramtin, Fish, Eleanor N.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929946/
https://ncbi.nlm.nih.gov/pubmed/27335323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160122
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