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CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1

The multistep, coordinated process of T-cell chemotaxis requires chemokines, and their chemokine receptors, to invoke signaling events to direct cell migration. Here, we examined the role for CCL5-mediated initiation of mRNA translation in CD4(+) T-cell chemotaxis. Using rapamycin, an inhibitor of m...

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Detalles Bibliográficos
Main Authors: Murooka, Thomas T., Rahbar, Ramtin, Platanias, Leonidas C., Fish, Eleanor N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384123/
https://ncbi.nlm.nih.gov/pubmed/18337562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-125039
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