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Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars

Mycobacterium tuberculosis (Mtb), the aetiological agent of tuberculosis, has evolved to scavenge nutrients from the confined environment of host macrophages with mycobacterial ATP-binding cassette (ABC) transporters playing a key role in nutrient acquisition. Mtb-UspC (Rv2318) is the solute-binding...

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Veröffentlicht in:Open Biol
Hauptverfasser: Fullam, Elizabeth, Prokes, Ivan, Fütterer, Klaus, Besra, Gurdyal S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929945/
https://ncbi.nlm.nih.gov/pubmed/27335320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160105
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