Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars

Mycobacterium tuberculosis (Mtb), the aetiological agent of tuberculosis, has evolved to scavenge nutrients from the confined environment of host macrophages with mycobacterial ATP-binding cassette (ABC) transporters playing a key role in nutrient acquisition. Mtb-UspC (Rv2318) is the solute-binding...

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Bibliographic Details
Published in:Open Biol
Main Authors: Fullam, Elizabeth, Prokes, Ivan, Fütterer, Klaus, Besra, Gurdyal S.
Format: Artigo
Language:Inglês
Published: The Royal Society 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929945/
https://ncbi.nlm.nih.gov/pubmed/27335320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160105
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