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Human neutrophil kinetics: modeling of stable isotope labeling data supports short blood neutrophil half-lives

Human neutrophils have traditionally been thought to have a short half-life in blood; estimates vary from 4 to 18 hours. This dogma was recently challenged by stable isotope labeling studies with heavy water, which yielded estimates in excess of 3 days. To investigate this disparity, we generated ne...

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書誌詳細
出版年:Blood
主要な著者: Lahoz-Beneytez, Julio, Elemans, Marjet, Zhang, Yan, Ahmed, Raya, Salam, Arafa, Block, Michael, Niederalt, Christoph, Asquith, Becca, Macallan, Derek
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929930/
https://ncbi.nlm.nih.gov/pubmed/27136946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-700336
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