Human neutrophil kinetics: modeling of stable isotope labeling data supports short blood neutrophil half-lives

Human neutrophils have traditionally been thought to have a short half-life in blood; estimates vary from 4 to 18 hours. This dogma was recently challenged by stable isotope labeling studies with heavy water, which yielded estimates in excess of 3 days. To investigate this disparity, we generated ne...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Lahoz-Beneytez, Julio, Elemans, Marjet, Zhang, Yan, Ahmed, Raya, Salam, Arafa, Block, Michael, Niederalt, Christoph, Asquith, Becca, Macallan, Derek
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2016
Fag:
Phagocytes, Granulocytes, and Myelopoiesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929930/
https://ncbi.nlm.nih.gov/pubmed/27136946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-700336
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