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Evaluation of transethnic fine mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations

There has been limited success in identifying causal variants underlying association signals observed in genome-wide association studies (GWAS). The use of 1000 Genomes Project (1KGP) allows the imputation to estimate the genetic information at untyped variants. However, long stretches of high linka...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Wang, Xu, Cheng, Ching-Yu, Liao, Jiemin, Sim, Xueling, Liu, Jianjun, Chia, Kee-Seng, Tai, E-Shyong, Little, Peter, Khor, Chiea-Chuen, Aung, Tin, Wong, Tien-Yin, Teo, Yik-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929869/
https://ncbi.nlm.nih.gov/pubmed/26130488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.150
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