Impact of Measurement Error on Testing Genetic Association with Quantitative Traits

Measurement error of a phenotypic trait reduces the power to detect genetic associations. We examined the impact of sample size, allele frequency and effect size in presence of measurement error for quantitative traits. The statistical power to detect genetic association with phenotype mean and vari...

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Detalhes bibliográficos
Main Authors: Liao, Jiemin, Li, Xiang, Wong, Tien-Yin, Wang, Jie Jin, Khor, Chiea Chuen, Tai, E. Shyong, Aung, Tin, Teo, Yik-Ying, Cheng, Ching-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901720/
https://ncbi.nlm.nih.gov/pubmed/24475218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087044
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