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Membrane-Localized Estrogen Receptor 1 Is Required for Normal Male Reproductive Development and Function in Mice
Estrogen receptor 1 (ESR1) mediates major reproductive functions of 17β-estradiol (E2). Male Esr1 knockout (Esr1KO) mice are infertile due to efferent ductule and epididymal abnormalities. The majority of ESR1 is nuclear/cytoplasmic; however, a small fraction is palmitoylated at cysteine 451 in mice...
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| Publicado no: | Endocrinology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4929544/ https://ncbi.nlm.nih.gov/pubmed/27145009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1085 |
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