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Membrane-localized Estrogen Receptor Alpha is Required for Normal Organ Development and Function
Steroid receptors are found in discrete cellular locations but it is unknown whether extra-nuclear pools are necessary for normal organ development. To assess this we developed a point-mutant estrogen receptor alpha (ERα) knock-in mouse (C451A) that precludes palmitoylation and membrane trafficking...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4062189/ https://ncbi.nlm.nih.gov/pubmed/24871949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.04.016 |
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