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Visualization of Neuregulin 1 ectodomain shedding reveals its local processing in vitro and in vivo
Neuregulin1 (NRG1) plays diverse developmental roles and is likely involved in several neurological disorders including schizophrenia. The transmembrane NRG1 protein is proteolytically cleaved and released as a soluble ligand for ErbB receptors. Such post-translational processing, referred to as ‘ec...
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| Yayımlandı: | Sci Rep |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4929465/ https://ncbi.nlm.nih.gov/pubmed/27364328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28873 |
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