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Visualization of Neuregulin 1 ectodomain shedding reveals its local processing in vitro and in vivo
Neuregulin1 (NRG1) plays diverse developmental roles and is likely involved in several neurological disorders including schizophrenia. The transmembrane NRG1 protein is proteolytically cleaved and released as a soluble ligand for ErbB receptors. Such post-translational processing, referred to as ‘ec...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4929465/ https://ncbi.nlm.nih.gov/pubmed/27364328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28873 |
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