α4-Integrin Antibody Treatment Blocks Monocyte/Macrophage Traffic to, Vascular Cell Adhesion Molecule-1 Expression in, and Pathology of the Dorsal Root Ganglia in an SIV Macaque Model of HIV-Peripheral Neuropathy

Traffic of activated monocytes into the dorsal root ganglia (DRG) is critical for pathology in HIV peripheral neuropathy. We have shown that accumulation of recently recruited (bromodeoxyuridine(+) MAC387(+)) monocytes is associated with severe DRG pathology and loss of intraepidermal nerve fibers i...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Lakritz, Jessica R., Thibault, Derek M., Robinson, Jake A., Campbell, Jennifer H., Miller, Andrew D., Williams, Kenneth C., Burdo, Tricia H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2016
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929389/
https://ncbi.nlm.nih.gov/pubmed/27157989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.03.007
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