Loss of intraepidermal nerve fiber density during SIV peripheral neuropathy is mediated by monocyte activation and elevated monocyte chemotactic proteins

BACKGROUND: Peripheral neuropathy (PN) continues to be a major complication of human immunodeficiency virus (HIV) infection despite successful anti-retroviral therapy. Human HIV-PN can be recapitulated in a CD8-depleted, simian immunodeficiency virus (SIV)-infected rhesus macaque animal model, chara...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Lakritz, Jessica R., Robinson, Jake A., Polydefkis, Michael J., Miller, Andrew D., Burdo, Tricia H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683776/
https://ncbi.nlm.nih.gov/pubmed/26683323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0456-8
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