Aberrant Promoter Methylation at CpG Cytosines Induce the Upregulation of the E2F5 Gene in Breast Cancer

PURPOSE: The promoter methylation status of cell cycle regulatory genes plays a crucial role in the regulation of the eukaryotic cell cycle. CpG cytosines are actively subjected to methylation during tumorigenesis, resulting in gain/loss of function. E2F5 gene has growth repressive activities; vario...

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Detalhes bibliográficos
Publicado no:J Breast Cancer
Main Authors: Ali, Arshad, Ullah, Farman, Ali, Irum Sabir, Faraz, Ahmad, Khan, Mumtaz, Shah, Syed Tahir Ali, Ali, Nawab, Saeed, Muhammad
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Breast Cancer Society 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929253/
https://ncbi.nlm.nih.gov/pubmed/27382388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4048/jbc.2016.19.2.133
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