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Spontaneous mutations and the origin and maintenance of quantitative genetic variation

Mutation and natural selection shape the genetic variation in natural populations. Here, we directly estimated the spontaneous mutation rate by sequencing new Drosophila mutation accumulation lines maintained with minimal natural selection. We inferred strong stabilizing natural selection on quantit...

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Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Huang, Wen, Lyman, Richard F, Lyman, Rachel A, Carbone, Mary Anna, Harbison, Susan T, Magwire, Michael M, Mackay, Trudy FC
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929002/
https://ncbi.nlm.nih.gov/pubmed/27213517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14625
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