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Spontaneous mutations and the origin and maintenance of quantitative genetic variation

Mutation and natural selection shape the genetic variation in natural populations. Here, we directly estimated the spontaneous mutation rate by sequencing new Drosophila mutation accumulation lines maintained with minimal natural selection. We inferred strong stabilizing natural selection on quantit...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Huang, Wen, Lyman, Richard F, Lyman, Rachel A, Carbone, Mary Anna, Harbison, Susan T, Magwire, Michael M, Mackay, Trudy FC
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929002/
https://ncbi.nlm.nih.gov/pubmed/27213517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14625
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