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Melatonin Signal Transduction Pathways Require E-Box-Mediated Transcription of Per1 and Per2 to Reset the SCN Clock at Dusk

Melatonin is released from the pineal gland into the circulatory system at night in the absence of light, acting as “hormone of darkness” to the brain and body. Melatonin also can regulate circadian phasing of the suprachiasmatic nucleus (SCN). During the day-to-night transition, melatonin exposure...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kandalepas, Patty C., Mitchell, Jennifer W., Gillette, Martha U.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928778/
https://ncbi.nlm.nih.gov/pubmed/27362940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157824
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