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Melatonin Signal Transduction Pathways Require E-Box-Mediated Transcription of Per1 and Per2 to Reset the SCN Clock at Dusk

Melatonin is released from the pineal gland into the circulatory system at night in the absence of light, acting as “hormone of darkness” to the brain and body. Melatonin also can regulate circadian phasing of the suprachiasmatic nucleus (SCN). During the day-to-night transition, melatonin exposure...

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Veröffentlicht in:PLoS One
Hauptverfasser: Kandalepas, Patty C., Mitchell, Jennifer W., Gillette, Martha U.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928778/
https://ncbi.nlm.nih.gov/pubmed/27362940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157824
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