Dexamethasone Drug Eluting Nanowafers Control Inflammation in Alkali-Burned Corneas Associated With Dry Eye

PURPOSE: To evaluate the efficacy of a controlled release dexamethasone delivery system for suppressing inflammation in an ocular burn + desiccating stress (OB+DS) model. METHODS: Nanowafers (NW) loaded with Dexamethasone (Dex, 10 μg) or vehicles (2.5% Methylcellulose; MC) were fabricated using hydr...

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Bibliografiske detaljer
Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Bian, Fang, Shin, Crystal S., Wang, Changjun, Pflugfelder, Stephen C., Acharya, Ghanashyam, De Paiva, Cintia S.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2016
Fag:
Nanotechnology and Regenerative Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928693/
https://ncbi.nlm.nih.gov/pubmed/27327581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19074
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